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The Cure Alliance Gets IRB Approval for “C3” Clinical Trial To Treat Deadliest Pancreatic Cancer AT SUNY Downstate

“C3,” a Mixture of three Generic Medicine Designed to Halt Superior Adenocarcinoma Pancreatic Cancer Strikes from the Lab to Human Trials

Mining the FDA record of 2500 authorised generic medication to deal with most cancers could possibly be a game-changer, saving years of analysis and billions of {dollars}. I’m grateful to the assist of The Cure Alliance.”

— Dr. F. Charles Brunicardi

MIAMI, FLORIDA, UNITED STATES, July 4, 2023/ — The Cure Alliance, 501(c)(3) non-profit, introduced as we speak State College of New York, Downstate Well being Science Heart has given Institutional Overview Board (IRB) approval to proceed with an FDA-cleared section II medical trial designed to halt superior stage adenocarcinoma pancreatic most cancers with “C3,” a novel mixture of three widely-available low-cost generic medication.

With commonplace remedy, this lethal most cancers has one of many lowest survival charges of any most cancers at 12%.

The FDA exempted “C3” from an IND overview (investigation of a brand new drug) expediting medical trials. This 12 months, The Cure Alliance supplied to totally fund a brand new two-year trial, and in April, SUNY Downstate Well being Science Heart accepted the sponsorship.

Underneath FDA rules, a proper IRB should nonetheless overview all particulars to make sure the medical trial is in compliance with relevant rules, moral requirements and institutional insurance policies and, most significantly, to safeguard the welfare and rights of human analysis individuals. IRB approval is the ultimate stage earlier than sufferers will be enrolled.

“The Cure Alliance is grateful for the meticulous efforts of the SUNY Downstate Well being Science Heart IRB committee in granting this approval. We’re trying ahead to the launch of this most vital trial with Dr. Mohan Preet as principal investigator,” mentioned Shelley Ross, President of The Cure Alliance who led the fundraising efforts for the “C3” undertaking with fellow board member and founder, Professor Camillo Ricordi, M.D., Director of Cell Transplant Heart and Director Emeritus, Diabetes Analysis Institute, College of Miami, Florida.

“C3” is the brainchild of Dr. F. Charles Brunicardi who has been engaged on a treatment for pancreatic most cancers for 28 years. He and his analysis crew have been first to develop the concept to display the FDA library of 2500 authorised medication utilizing “super-promoters-of-cancer targets” to find out if any mixture of generic medication would halt adenocarcinoma pancreatic most cancers. “C3” is a results of that search.

Dr. Brunicardi presently serves as Senior Vice President and Dean, Faculty of Medication at SUNY Downstate Well being Science Heart. He has embraced the braveness of the medical investigators, impartial of him, to forge forward with the trial at SUNY Downstate Well being Science Heart.

“Mining the FDA record of generic medication to deal with most cancers could possibly be a game-changer, saving years of analysis and billions of {dollars}. Together with my colleagues, I’m grateful to The Cure Alliance donors who’ve made this trial doable.”

Dr. Brunicardi brings greater than three many years of expertise in tutorial medication and affected person care, serving on the school at three medical colleges and as Chair of two departments of Surgical procedure and Vice-Chair of one other. Dr. Brunicardi has been perennially listed among the many nation’s “Prime Medical doctors” by Citadel Connolly, Ltd. He has revealed 318 papers and has served because the Editor-in-Chief of Schwartz’s Rules of Surgical procedure since 2000. The most up-to-date, the eleventh version of Schwartz’s Rules of Surgical procedure, is taken into account the world’s main surgical textbook

Enrollment particulars for the “C3 “trial will quickly be posted on

The Cure Alliance is a boutique 501(c)(3) non-profit group of high scientists, researchers, medical medical doctors and innovators, plus those that assist our efforts to finish human struggling by creating cures for continual, debilitating and deadly ailments. Our #1 mission is to assist transfer potential cures from the laboratory to the affected person’s bedside.

Shelley Ross
The Cure Alliance
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